The NUC16R-D5 VER1.1 is a 120 mm × 120 mm Industrial Motherboard designed for embedded and industrial applications. Powered by Intel® Alder Lake-N and Twin Lake-N series processors, it provides reliable computing performance for industrial control, network security, and embedded system projects.
Designed with 6 × Intel® I225/I226 2.5GbE LAN ports, 2 × RS232 serial ports with optional RS485/RS422 support, USB 3.0 and USB 2.0 connectivity, HDMI and DP display outputs supporting up to 4K @ 60 Hz, and SATA 3.0 plus M.2 Key-M 2280/2242 PCIe/SATA storage, this product supports flexible system integration for soft routers, network security appliances, industrial control systems, and cloud terminals.
With 120 mm × 120 mm dimensions, industrial-grade reliability, and flexible configuration options, the NUC16R-D5 VER1.1 provides a dependable platform for OEM and ODM projects.

Top view of the CoreIPC NUC16R-D5 VER1.1 industrial motherboard.
Key Features
- Intel® Alder Lake-N and Twin Lake-N series processors
- 120 mm × 120 mm form factor
- 6 × Intel® I225/I226 2.5GbE LAN ports with Wake-on-LAN and PXE support
- 1 × HDMI 1.4 and 1 × DP, supporting simultaneous or independent 4K @ 60 Hz display
- 1 × Mini-PCIe slot supporting Wi-Fi / 4G modules and optional mSATA configuration
- 1 × SATA 3.0 connector and 1 × M.2 Key-M 2280/2242 slot supporting PCIe/SATA SSDs
- Windows 10 / Windows 11 / Linux

Bottom view of the CoreIPC NUC16R-D5 VER1.1 industrial motherboard.

I/O ports of the CoreIPC NUC16R-D5 VER1.1 industrial motherboard.

Six LAN ports of the CoreIPC NUC16R-D5 VER1.1 industrial motherboard.
Q1. What processor platform does the NUC16R-D5 support?
The NUC16R-D5 supports Intel® Alder Lake-N and Twin Lake-N series processors. The standard specification integrates an Intel® Celeron® N100 quad-core processor.
Q2. What memory does the NUC16R-D5 support?
The motherboard provides 1 × DDR5 SO-DIMM slot supporting single-channel DDR5 4800 MHz memory with a maximum capacity of 16 GB.
Q3. What display interfaces are available?
The NUC16R-D5 provides 1 × HDMI 1.4 and 1 × DP interface. Both interfaces support up to 4K @ 60 Hz and can operate simultaneously or independently.
Q4. What storage interfaces does the motherboard provide?
The motherboard provides 1 × SATA 3.0 connector with transfer rates up to 6 Gbps and 1 × M.2 Key-M 2280/2242 slot supporting PCIe/SATA SSDs. The SATA interface is shared with mSATA and is selectable.
Q5. Does the NUC16R-D5 support Mini-PCIe, Wi-Fi, and 4G expansion?
Yes. It provides 1 × Mini-PCIe slot supporting Wi-Fi and 4G modules by default and can be configured via hardware to support mSATA. A SIM card slot is also provided.
Q6. How many LAN and USB interfaces does the motherboard support?
The NUC16R-D5 supports 6 × Intel® I225/I226 2.5GbE LAN ports with Wake-on-LAN and PXE. It also supports up to 2 × USB 3.0 and 5 × USB 2.0 ports.
Q7. Does the NUC16R-D5 support RS485 communication?
The standard configuration provides 2 × RS232 serial ports. RS485 support requires hardware modification; COM1/JCOM1 can optionally support RS485, while JCOM2 can be configured for RS485/RS422.
Q8. Which operating systems are supported?
The NUC16R-D5 supports Windows 10, Windows 11, and Linux.
CoreIPC provides reliable industrial computing platforms with long-term product availability and flexible customization services for embedded and industrial applications.
Why Choose CoreIPC
- Six 2.5GbE LAN Ports
- Flexible Mini-PCIe Expansion
- HDMI and DP Display Support
- Optional RS485 / RS422
- Fanless Cooling Design
- -10°C to 60°C Operation